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Map of proliferative blood disorders. 

By Ariella Coler-Reilly @ariellastudies

#Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
proliferative blood ... disorders. ... ariellastudies #Algorithm ... #classification ... proliferative #blood
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen, leading to complement ... - Red blood cell ... with mismatched blood ... Complement activation ... #Classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
hematological disorders ... to Autoimmune Disorders ... • Low serum C4 complement ... connective tissue disorder ... #classification
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Blood Loss ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... Non-lmmune #Anemia #Classification
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease 3 Types ... lymphoproliferative disorder ... Immunoglobulin M (IgM) • Blood ... sensitize red blood ... temperatures by fixing complement
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Urticaria and hypocomplementemia ... pulses, bruis, or blood ... Large Vessel: Blood ... against MPO • Complement ... #rheumatology #classification
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... proportion of the red blood ... three peripheral blood ... or a peripheral type ... that involves disorders
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... ) • Endocrine disorders ... Kikuchi disease • Type-I ... RNP antibodies, Complement
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
or plasma cell disorder ... guide subtype classification ... tubulopathy) - Complement ... vasculitis Types
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
2022-lab-advisory-CLARIFICATION-CDC_Publishes_Non-variola_Orthopoxvirus_PCR_Testing_Procedure ... should use this algorithm ... smallpox-diagnostic-algorithm-poster ... The type of specimen ... Whole blood alone