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diagnosis rheumatology allergy glomerular hypersensitivity nephrology nephrotic reactions testing workup agglutinin anemia causes clinicopathology cold comparison cryoglobulinemia cryoglobulins differential erythematosus
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
during hemolytic disease ... Type Ill - IgG and ... Complement activation ... #Classification ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... reaction, Haemolytic disease ... they activate complement ... #allergy #table ... #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... hematological disorders ... to Autoimmune Disorders ... • Low serum C4 complement ... #classification
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... pulmonary Langerhans cell ... Hypertension #PHTN #Classification
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
3 Types of Cold ... lymphoproliferative disorder ... infection, autoimmune disorder ... lymphoid malignancy (CLL ... temperatures by fixing complement
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
for glomerular disease ... decreased red cell ... or alternative complement ... of glomerular disease ... cryoglobulinemias (types
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Classification: ... ) • Endocrine disorders ... • Type-I Interferonopathies ... RNP antibodies, Complement
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
for glomerular disease ... decreased red cell ... or alternative complement ... cryoglobulinemias (types ... #glomerular #disease
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
basis: Th2 & Treg cell-mediated ... - IgG4+ plasma cell ... • Pancreas: Type ... - ↑ IgE, ↓ complement ... • Classification
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
refers to kidney disease ... disorder that does ... guide subtype classification ... tubulopathy) - Complement ... vasculitis Types
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