9 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... 1 (50%-80%), type ... endocarditis (90%) - Dr ... #Low #Complement ... #differential #hematology
Subtypes of Serum Proteins

Pre-albumin (Transthyretin)
Albumin
Globulins
 • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
IgA, RF, CRP Dr ... Proteins #Subtypes #algorithm ... #classification ... #Types #hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... Types: • Type ... • Low serum C4 complement ... #classification ... #rheumatology #
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... - Most common type ... Hemorrhagic → leading ... water #Shock #Classification ... #management #criticalcare
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... • Most common type ... Hemorrhagic → leading ... #Types #diagnosis ... #management #cold
Hepatic Encephalopathy - Diagnosis and Management Summary
Definition:
 • Alteration in brain function manifested by neuropsychiatric symptoms
Diagnosis and Management ... Encephalopathy #Grading ... #Classification ... #Diagnosis #Management ... #treatment #hepatology
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Pancreas: Type ... - ↑ IgE, ↓ complement ... • Classification ... IGG4 #Diagnosis #Management ... #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Cytopenia: 2% • Hypocomplementemia ... PAH Skin: • Dry ... Nephrogenic DI Hematologic ... #Diagnosis #Management
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
meet criteria for hematologic ... Proteinuria >1.5 g/day ... guide subtype classification ... tubulopathy) - Complement ... vasculitis Types