18 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... - CHAMPS Mnemonic ... Chain deposition disease ... 1 (50%-80%), type ... #Low #Complement
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... antigen, leading to complement ... during hemolytic disease ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of types ... antigens, leading to complement ... reaction, Haemolytic disease ... they activate complement ... allergy #table #classification
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... for glomerular disease ... or alternative complement ... of glomerular disease ... cryoglobulinemias (types
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... for glomerular disease ... or alternative complement ... cryoglobulinemias (types ... diagnosis #initial #testing
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... Types: • Type ... • Type III Often ... • Low serum C4 complement ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Granulomatous disease ... against MPO • Complement ... #rheumatology #classification
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Disease ... 3 Types of Cold ... Positive Coombs testing ... post infectious setting ... temperatures by fixing complement
Amyloidosis - Summary
Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
configuration Types ... the extent of disease ... Immunoglobulin light chains ... Immunoglobulin light chains ... typing Cardiac Testing
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm
Lifestyle  Modifications (Diet and Exercise) -> Start
Type 2 Diabetes ... and Management Algorithm ... PCOS), Pancreatic Disease ... Targets #Management #algorithm ... #DM2 #DMII #Classification