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diagnosis hematology differential rheumatology disease glomerular nephrology nephrotic vasculitis workup agglutinin amyloid amyloidosis anemia antiarrhythmics blood cardiology causes classes clinicopathology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... - CHAMPS Mnemonic ... 1 (50%-80%), type ... #Low #Complement ... #CHAMPS #Mnemonic
Hypokalemia - Differential Diagnosis Poor Intake - Starvation - Anorexia GI Losses - Vomiting / NG
tubular acidosis (Types ... and 2, but not type ... 4) - Salt wasting ... Differential #Diagnosis #Low ... Potassium #Table #Classification
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... deficiency • Low ... #Deficiency #Testing ... #Algorithm #hematology
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... in monitoring low-level ... or alternative complement ... cryoglobulinemias (types ... #glomerular #testing
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... • Type III Often ... factor level • Low ... serum C4 complement ... #classification
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... in monitoring low-level ... or alternative complement ... cryoglobulinemias (types ... diagnosis #initial #testing
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
moving back to resting ... Phase 4 - True Resting ... Vaughan Williams Classification ... activation (↓ cAMP ... #Pharmacology #Classification
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Disease 3 Types ... originate from a low-grade ... Positive Coombs testing ... post infectious setting ... temperatures by fixing complement
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... #rheumatology #classification
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
fibrils formed from low-molecular-weight ... configuration Types ... Cardiac: • LVH, low-voltage ... Immunoglobulin light chains ... typing Cardiac Testing
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