8 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... antigen, leading to complement ... Complement activation ... sclerosis #Hypersensitivity ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
of hypersensitivity ... antigens, leading to complement ... they activate complement ... Graft rejection #hypersensitivity ... allergy #table #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Syndrome: • Clinical ... Types: • Type ... • Low serum C4 complement ... vasculitis • Hypersensitivity ... #classification
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... Pathogenesis and clinical ... activates the complement ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction
Comprehensive pathogenesis of IgA Nephropathy (i.e Berger’s Disease). 

IgA Nephropathy is the most common cause of
- What type of Hypersensitivity ... Relationship of complement ... BergersDisease #clinical ... PediatricNephrology #Hypersensitivity
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
specific) COMMON CLINICAL ... • Pancreas: Type ... Essential Criteria: Clinical ... - ↑ IgE, ↓ complement ... • Classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I ... RNP antibodies, Complement
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Clinical Clues: ... guide subtype classification ... tubulopathy) - Complement ... vasculitis Types