16 results
diagnosis differential hematology nephrology disease glomerulonephritis lupus management nephritis nephrotic renal testing workup agglutinin anemia champs cold cryoglobulinemia cryoglobulins erythematosus
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... TerrierBen #Hypocomplementemic ... Pathophysiology #Rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement ... #differential #hematology
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
Vasculitis - Break ... can affect any type ... Anti-GBM = anti–glomerular ... #Diagnosis #Rheumatology ... Medium #Large #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Skin, glomeruli ... : - Kidneys: glomerular ... against MPO • Complement ... differential #diagnosis #rheumatology ... #classification
Lupus Nephritis Classification Algorithm #Lupus #Nephritis #Classification #Algorithm #diagnosis #differential #types #rheumatology #nephrology #renal
Lupus Nephritis Classification ... Algorithm #Lupus ... #Algorithm #diagnosis ... #differential #types ... #rheumatology #
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... • Low serum C4 complement ... #classification ... #rheumatology # ... vasculitis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
evaluated for glomerular ... monitoring low-level glomerular ... or alternative complement ... for ANCA-related vasculitis ... cryoglobulinemias (types
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... • Kidneys: Non-glomerular ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic ... Differential #Diagnosis #Rheumatology
Subtypes of Serum Proteins Pre-albumin (Transthyretin) Albumin Globulins • Alpha-1: Alpha-1 antitrypsin, Serum amyloid A, Ceruloplasmin, Corticosteroid-binding globulin (Transcortin),
Proteins #Subtypes #algorithm ... #classification ... #Types #hematology
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