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rheumatology differential management medium small anca cryoglobulinemia cryoglobulins ddxof erythematosus gammopathy igg4 lupus mgrs monoclonal renal rheum significance size sjogrens
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
#Diagnosis # ... IM #Rheum #Vasculitis ... Small #Medium #Large ... #Vessel #Size #Classification ... #Differential #Algorithm
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
involvement by large ... Large vessel vasculitis ... can affect any type ... #Diagnosis #Rheumatology ... #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Urticaria and hypocomplementemia ... , arthritis LARGE ... Vessel Size: • Large ... against MPO • Complement ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Types: • Type ... Labs/Diagnosis: ... • Low serum C4 complement ... Cryoglobulins #diagnosis ... #types #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Differential Diagnosis ... Kikuchi disease • Type-I ... the small and large
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... IV RTA, TYPE I ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... cell lymphoma • Large
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
• Pancreas: Type ... aortitis, mimics vasculitis ... breast, skin DIAGNOSIS ... - ↑ IgE, ↓ complement ... • Classification
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis ... Types of MGRS-Associated ... #Significance #Diagnosis
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