141 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis (>90%) S - Systemic ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Approach to Nausea / Vomiting - Differential Diagnosis Framework
 • Gastrointestinal 
    -
Approach to Nausea ... Central Nervous System ... Disorders • Other Causes ... Differential #Diagnosis #Classification ... #Systems
Commonly Used Clinical Grading Systems
 • Edema Grading Scale
 • Hepatic Encephalopathy Grading (West Haven Criteria)
Commonly Used Clinical ... Grading Systems ... Criteria) • Systolic ... DharSaty #Grading #Systems ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Erythematosus Clinical ... anticoagulant • Complement ... Criteria #SLE #Systemic
Inflammatory Cascade: Pathogenesis and Clinical Findings
Continued Innate Immunity
 • Phagocytosis: (main mechanism) neutrophils and macrophages engulf
Pathogenesis and Clinical ... dead tissue • Complement ... System: opsonize ... activation of complement ... system • Cell-mediated
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Local and systemic ... antigen, leading to complement ... Complement activation ... arthritis, and systemic ... Hypersensitivity #Types #Classification
C5-C9 Deficiency - Pathogenesis and Clinical Findings
Note:
 • Risk of invasive meningococcal disease is 1000-10000x higher
Pathogenesis and Clinical ... infections • Clinical ... response: The complement ... cell membranes -> Critical ... susceptibility to systemic
Causes, classification and compensatory responses to shock.

Shock can be caused by any pathological process that leads
Causes, classification ... Shock can be caused ... shock is often clinically ... renin–angiotensin–aldosterone system ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... antigens, leading to complement ... they activate complement ... glomerulonephritis, Systemic ... allergy #table #classification