10 results
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... cellular antigen, leading ... to complement activation ... Complement activation ... #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
of hypersensitivity ... cell antigens, leading ... to complement activation ... they activate complement ... allergy #table #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... Types: • Type ... • Low serum C4 complement ... vasculitis • Hypersensitivity ... #classification
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity ... degranulation, leading ... because T-Cell activation ... #Hypersensitivity ... #Classification
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... - Most common type ... Hemorrhagic → leading ... water #Shock #Classification
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... • Most common type ... Hemorrhagic → leading ... #Types #diagnosis
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... IL-1 and IL-6, leading ... nervous system (CNS) dysfunction ... • Drug-induced hypersensitivity ... MAS #Macrophage #Activation
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- Organ dysfunction ... progressive organ dysfunction ... • Pancreas: Type ... - ↑ IgE, ↓ complement ... • Classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I ... mild cognitive dysfunction ... Chronic B-cell activation
Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
guide subtype classification ... tubulopathy) - Complement ... pathway activation ... vasculitis Types