8 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... cell antigens, leading ... glomerulonephritis, Systemic lupus ... #classification
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Discontinuation of causal ... 80% - Low complement ... Usual therapeutic management ... sle #comparison #table
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... Complement activation ... , and systemic lupus ... Hypersensitivity #Types #Classification ... Diagnosis #Reactions #Table
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic Lupus ... Encephalopathy, Cognitive Dysfunction ... autoantibodies that will cause ... inflammation, leading ... cerebritis #diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... #rheumatology #classification
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... Types #diagnosis #management ... warm #wet #dry #table
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... (e.g. systemic lupus ... diagnosis #types #classification
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... Pathophysiology: 1) T-cell dysfunction ... Self-limiting, chronic but stable ... skin (16-32%): lupus ... Sarcoidosis #Diagnosis #Management