12 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... types of hypersensitivity ... Allergen-specific lgE causes ... #allergy #table ... #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... Complement activation ... #Types #Classification ... Allergy #Diagnosis #Reactions ... #Table
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
10% of all lupus cases ... 90% - Low complement ... Positive in 60-80% of cases ... 80% - Low complement ... #comparison #table
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... > 0.5 g/24 hr, Class ... lupus nephritis, Class ... anticoagulant • Complement ... #Criteria #SLE
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
Hypersensitivity ... cell surfaces causes ... exposure to allergen causes ... #Hypersensitivity ... #Types #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... disease, drug reactions ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
• Secondary Causes ... Splenomegaly - CTD (SLE ... Vasculitis: • Hypersensitivity ... Associated - SLE ... fever • Drug reactions
Shock - Differential Diagnosis by Classification
Reflex Syncope 
 - Vasovagal syncope
   • Prolonged standing
Differential Diagnosis by Classification ... Carotid sinus hypersensitivity ... Differential #Diagnosis #Classification ... #Table #Causes
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... See below for table ... helpful paper complements ... #Differential #Table
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... • Low serum C4 complement ... vasculitis • Hypersensitivity ... erythematosus (SLE ... diagnosis #types #classification