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diagnosis differential rheumatology causes lupus workup comparison erythematosus glomerular nephrology nephrotic potassium systemic vasculitis acidosis allergy champs clinicopathology criteria cryoglobulinemia
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Hypokalemia - Differential Diagnosis Poor Intake - Starvation - Anorexia GI Losses - Vomiting / NG
and 2, but not type ... 4) - Salt wasting ... Differential #Diagnosis #Low ... #Potassium #Table ... #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... they activate complement ... #allergy #table ... #classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... > 0.5 g/24 hr, Class ... lupus nephritis, Class ... anticoagulant • Complement ... #Criteria #SLE
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... factor level • Low ... serum C4 complement ... erythematosus (SLE ... #classification
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... complement - Rare ... 60-80% - Low ... complement - 50 ... #comparison #table
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Familial renal Mg wasting ... Differential #Diagnosis #Low ... #Magnesium #Table ... #Classification ... #Causes #Workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... against MPO • Complement ... (Low levels mixed ... vasculitis, and SLE ... #rheumatology #classification
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... in monitoring low-level ... or alternative complement ... cryoglobulinemias (types ... #glomerular #testing
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low ... complements and ... Skin Disease Classification ... Kikuchi disease • Type-I ... , lymphopenia, low
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