12 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
: Summary Type ... conjunctivitis Type ... Gravis, Graves' Disease ... Type III Hypersensitivity ... #Allergy #Allergic
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... antigen, leading to complement ... during hemolytic disease ... Complement activation ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... types of hypersensitivity ... reaction, Haemolytic disease ... they activate complement ... #allergy #table
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement
Eosinophilia - Differential Diagnosis Algorithm
Idiopathic Eosinophilia
Primary Eosinophilia:
 • Primary hypereosinophilic syndrome
 • Eosinophilic Leukemia
 • MPN/MDS
Differential Diagnosis Algorithm ... histiocytosis • Allergic ... , Eczema, Drug Hypersensitivity ... Differential #Diagnosis #Algorithm ... #allergy
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
Type II Hypersensitivity ... activates the complement ... cell surfaces #Type2 ... #Type2 #HypersensitivityReaction ... #Allergy #Immunology
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy
Mild Reaction - Itching, Minor rash
Use carbapenem Type ... If infectious disease ... Type II-IV HSR ... and Infectious Disease ... #Prescription #algorithm
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... Types: • Type ... • Type III Often ... • Low serum C4 complement ... vasculitis • Hypersensitivity
Comprehensive pathogenesis of IgA Nephropathy (i.e Berger’s Disease). 

IgA Nephropathy is the most common cause of
(i.e Berger’s Disease ... common in Liver disease ... - What type of Hypersensitivity ... Relationship of complement ... PediatricNephrology #Hypersensitivity
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
Ischemic heart disease ... event, follow ACC algorithm ... : - Known CV disease ... Risk Stratify Type ... What is the type