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diagnosis differential management causes rheumatology comparison classification treatment cardiology hematology allergy glomerulonephritis hypersensitivity nephrology pediatrics vasculitis anemia autoimmune clinical dermatology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... antigen, leading to complement ... during hemolytic disease ... Complement activation ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... antigens, leading to complement ... reaction, Haemolytic disease ... they activate complement ... #allergy #table
Summary table of autoimmune diseases and the specific antibody related to the disease. Visit gramproject.com for
Summary table of ... autoimmune diseases ... related to the disease ... #diagnosis #algorithm ... #table #autoimmune
Effect of Selected Diseases on Complement Levels - C3, C4 • SLE C3 ↓ C4 ↓↓
Effect of Selected Diseases ... on Complement Levels ... C4 ↓↓ • MCGN type ... ThePeanutKidney #Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... differential #diagnosis #algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Granulomatous disease ... atherosclerotic disease ... against MPO • Complement
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... Types: • Type ... arthritis) • Types ... • Type III Often ... • Low serum C4 complement
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Differential Diagnosis Table ... Cold Agglutinin Disease ... Mixed-type AIHA ... Differential #Diagnosis #Table
The Diagnostic Approach to Hyperkalemia Drugs - Amiloride - Spironolactone - Triamterene - Trimethoprim - Pentamidine -
obstruction _ pHA type ... I, type II - ... Sickle cell disease ... _ pHA type II ... #Hyperkalemia #Algorithm
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