13 results
diagnosis differential rheumatology types allergy hypersensitivity central clinicopathology comparison cryoglobulinemia cryoglobulins dermatology erythematosus gammopathy gi glomerulonephritis hematology igg4 ileitis laboratory
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... , drug reactions ... against MPO • Complement ... #rheumatology #classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... , Haemolytic disease ... they activate complement ... types #allergy #table ... #classification
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
atherosclerotic disease ... , drug reactions ... most important diseases ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
during hemolytic disease ... Complement activation ... Hypersensitivity #Types #Classification ... Allergy #Diagnosis #Reactions ... #Table
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... Rheumatologic, Vasculitides ... , IBD, Celiac disease ... syndrome, POEMS • Reaction ... Exercise, Allergic reactions
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
beyond Crohn’s disease ... spondyloarthropathies, vasculitides ... See below for table ... helpful paper complements ... #Differential #Table
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... • Low serum C4 complement ... • IgA vasculitis ... • Vasculitis ... diagnosis #types #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Classification: ... ANCA-associated vasculitis ... • Mesenteric vasculitis ... RNP antibodies, Complement
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
IGG-4 RELATED DISEASE ... fibroinflammatory disease ... aortitis, mimics vasculitis ... - ↑ IgE, ↓ complement ... • Classification
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