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diagnosis differential rheumatology management renal bronchiectasis classification dermatology gammopathy glomerulonephritis hemoptysis massive mgrs monoclonal petechiae petechial physicalexam progressive prs rapidly
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... With associated pulmonary ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
progressing GN • New pulmonary ... tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
Causes of Hemoptysis ... • Bronchitis Diffuse ... Vasculitis Infection ... Vasculitis • ... #Causes #Pulmonary
Bronchiectasis: diagnosis and management Causes of localized -> diffuse bronchiectasis Foreign body, Bronchial stenosis (tumor, .. ),
management Causes ... of localized -> diffuse ... #Differential #workup ... #algorithm #pulmonary
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
progressing GN • New pulmonary ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic ... Differential #Diagnosis #Rheumatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... mononeuritis multiplex WORKUP ... Goodpasture's cause ... leading to diffuse ... hemorrhage (DAH) • Diffuse
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... Infection - Vasculitis ... deficiency Work ... #Causes #dermatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... , INC risk PE, Pulmonary ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
kidney disease caused ... meet criteria for hematologic ... Diagnostic Workup ... tubulopathy) - Complement ... formation causing vasculitis
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