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diagnosis classification differential rheumatology causes hematology hypersensitivity pathophysiology reactions table vasculitis arthritis champs comparison cryoglobulinemia cryoglobulins disease erythematosus high hyperkalemia
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... S - Systemic Lupus ... #Low #Complement
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... antigen, leading to complement ... Complement activation ... , and systemic lupus
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... antigens, leading to complement ... they activate complement ... glomerulonephritis, Systemic lupus ... #allergy #table
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... : • Systemic Lupus ... Erythematosus (SLE ... sickness #TypeIII #Type3 ... HypersensitivityReaction #Allergy
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... • Systemic Lupus ... • Acne • Allergy ... Hodgkin's Lymphoma #Diffuse
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Kikuchi disease • Type-I ... pneumonitis • Diffuse ... enteropathy, and diffuse
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... Types: • Type ... • Low serum C4 complement ... (e.g. systemic lupus ... erythematosus (SLE
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Urticaria and hypocomplementemia ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... vasculitis, and SLE
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... erythematosus (SLE ... Tests for All Types ... Screening Tests for Diffuse ... Additional Tests for Diffuse
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
diseases: syßtemic lupus ... erythematosus (SLE ... Pseudohypoaldosteronism type ... Tubulointerstitial diseases: SLE ... pseudohypoaldosteronism type
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