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diagnosis differential rheumatology causes cryoglobulinemia cryoglobulins erythematosus glomerulonephritis hemoptysis massive mimics progressive rapidly renal rpgn syndromes systemic types vasculitides
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
Pulmonary Renal ... Diagnosis Framework Diffuse ... anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... - Normal Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement ... , and SLE) • Urinalysis ... #rheumatology #classification
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
Differential Diagnosis Algorithm ... • Bronchitis Diffuse ... Vasculitis Infection ... Vasculitis • ... Lupus Erythematosus
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus ... With associated pulmonary ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... pneumonitis • Diffuse ... enteropathy, and diffuse
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... • Low serum C4 complement ... (e.g. systemic lupus ... erythematosus (SLE ... diagnosis #types #classification
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