6 results
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
• Class Ill - Focal ... LN (<50% of glomeruli ... • Class IV - Diffuse ... LN (>50% of glomeruli ... ) Diffuse segmental
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm

DIFFUSE
Scarring - Irreversible-biopsy required
 • Lupus
Diagnosis Algorithm ... DIFFUSE Scarring ... Irreversible-biopsy required • Lupus ... • Discoid lupus ... Differential #Diagnosis #Algorithm
Summary of characteristic abnormalities of selected glomerular diseases
Light Microscopy (LM) - Immunofluorescence Microscopy (IM) - Electron
abnormalities of selected glomerular ... /nephritis • Lupus ... /RPS class IV (diffuse ... change disease • Focal ... pathology #comparison #table
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Summary table of ... they activate complement ... chain causing local ... glomerulonephritis, Systemic lupus ... types #allergy #table
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
- Local and systemic ... antigen, leading to complement ... Complement activation ... , and systemic lupus ... Diagnosis #Reactions #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis - Skin, glomeruli ... inflammation Others: • Lupus ... : - Kidneys: glomerular ... such as systemic lupus ... against MPO • Complement