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diagnosis rheumatology classification differential vasculitis ana antibodies antinuclear arthritis cryoglobulinemia cryoglobulins disease erythematosus hematology laboratory lymphomas lymphoproliferative nonhodgkin pathophysiology rheumatic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(SLE), Sjogren's ... • Nucleolar: Diffuse ... (SLE), Systemic ... (SLE), Systemic ... Lymphoproliferative Disorders
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low ... complements and ... , lymphopenia, low ... #Systemic #Lupus
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders ... site in lymphatic system ... with lymphatic system ... lymphadenopathy more diffuse ... involvement, irregular pattern
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... factor level • Low ... serum C4 complement ... (e.g. systemic ... lupus erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
lupus erythematosus ... - (C-ANCA) pattern ... against MPO • Complement ... (Low levels mixed ... vasculitis, and SLE
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
affected joint • Systemic ... lupus erythematosus ... Screening Tests for Diffuse ... metabolic or endocrine disorders ... chest wall, and low
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