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diagnosis causes dermatology rheumatology alopecia hairloss hematology skinrash classification inflammatory pulmonary ana antibodies antinuclear arthritis focal joint monoarticular msk neurology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... Erythematosus ( ... #Low #Complement ... Mnemonic #diagnosis #differential
Causes of Hemoptysis - Differential Diagnosis Algorithm Massive Hemoptysis (>I00 mL in 24 hours) • Malignancy •
of Hemoptysis - Differential ... Diagnosis Algorithm ... • Bronchitis Diffuse ... • Pulmonary Vasculitis ... • Lupus Erythematosus
Small Vessel Vasculitides • Granulomatosis with polyangiitis - Granulomatous manifestations (e.g., nasal crusting, destructive sinusitis, pulmonary
Small Vessel Vasculitides ... Cryoglobulinemic vasculitis ... viruses. systemic lupus ... erythematosus, ... #vasculitis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... inflammation Others: • Lupus ... such as systemic lupus ... erythematosus, ... against MPO • Complement
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... permanent alopecia Differential ... pneumonitis • Diffuse ... enteropathy, and diffuse ... RNP antibodies, Complement
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus ( ... erythematosus ( ... • Nucleolar: Diffuse ... erythematosus ( ... rheumatology #diagnosis #differential
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Diagnosis Algorithm ... • Systemic Lupus ... Erythematosus ... #Diagnosis #Algorithm
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Definition: Diffuse ... symptomatology Differential ... Complex: Systemic lupus ... erythematosus, ... anti-CCP • CXR (diffuse
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
and Focal) Differential ... Diagnosis Algorithm ... erythematosus ... • Discoid lupus ... erythematosus
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus ... Glomerulonephritis #Vasculitis ... #differential # ... diagnosis #algorithm
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