8 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... 1 (50%-80%), type ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... #Low #Complement
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... lupus erythematosus ... #classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... they activate complement ... glomerulonephritis, Systemic ... lupus erythematosus ... allergy #table #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Skin Disease Classification ... Kikuchi disease • Type-I ... • Kidney biopsy ... #Systemic #Lupus
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... associated with systemic ... Perform Kidney Biopsy ... Nephritis #diagnosis #algorithm ... #biopsy #indications
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... lupus erythematosus ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary gland) biopsy ... Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... salivary gland) biopsy
Causes of Hyperkalemia
l. Pseudohyperkalemia
  A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis
  B.
Causes of Hyperkalemia ... lupus erythematosus ... (SLE), sickle cell ... High #Potassium #Classification ... #Causes