10 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... S - Systemic Lupus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Post-strep GN, Lupus ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... 90% - Low complement ... constitutional symptoms • Treatment ... 80% - Low complement ... life-threatening • Treatment
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... 80% - Low complement ... life-threatening • Treatment ... Lupusreference #SLE #lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... inflammation Others: • Lupus ... such as systemic lupus ... against MPO • Complement
Treatment Algorithm for Active Proliferative Lupus Nephritis (Class III/IV or Mixed Class III/IV + V)
Induction Therapy
Treatment Algorithm ... Proliferative Lupus ... Protective Measures #Treatment ... #Algorithm #Proliferative ... #Lupus #Nephritis
Algorithm for the Treatment of Membranous Lupus Nephritis
Sub-nephrotic-range proteinuria (<3.5g/d, normal serum albumin) and Preserved kidney
Algorithm for the ... Treatment of Membranous ... Lupus Nephritis ... #Membranous #Lupus ... #Nephritis #Algorithm
Lupus Nephritis Treatment Algorithm

DOI: 10.1159/000511268

#Lupus #Nephritis #Treatment #Algorithm #management #nephrology
Lupus Nephritis ... Treatment Algorithm ... 10.1159/000511268 #Lupus ... #Nephritis #Treatment ... #Algorithm #management
Our approach to the diagnosis and initial management of patients with suspected HIT. Our approach is
imprecise, and complemented ... and to adjust treatment ... Thrombocytopenia #Algorithm
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... Epidemiology: -10% of all lupus ... 90% - Low complement ... constitutional symptoms • Treatment ... rheumatology #diagnosis #treatment