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diagnosis rheumatology erythematosus lupus vasculitis criteria cryoglobulinemia cryoglobulins differential eularacr granuloma majocchis management microscopy photo rubrum sjogrens syndrome trichophyton types
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Erythematosus Clinical ... Constitutional domain: Fever ... anticoagulant • Complement ... #Criteria #SLE
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Vasculitis: • Fevers ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... Syndrome: • Clinical ... • Low serum C4 complement ... diagnosis #types #classification
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... salivary ducts Clinical ... phenomenon (16%) MSK
Majocchi’s Granuloma due to Trichophyton rubrum This is GMS stain and culture of a skin biopsy
No fever. ... tissues - mainly caused ... recommended as sole ... - Systemic Rx ... Competent and compromised
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