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diagnosis hematology rheumatology genetics iem inbornerrors laboratory metabolism neonatology nicu pediatrics peds table vasculitis anemia bronchiectasis clinicopathology disorders erythematosus glomerulonephritis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Bronchiectasis: diagnosis and management Causes of localized -> diffuse bronchiectasis Foreign body, Bronchial stenosis (tumor, .. ),
RA, Sjögren, SLE ... diagnosis #management #Differential ... #workup #algorithm
A schema of the pathophysiology of the inborn errors of metabolism, excluding complex storage diseases. Helps
schema of the pathophysiology ... connections and pathophysiology ... See the lab values ... #Diagnosis #Algorithm ... #Differential #
Diagnostic algorithm for the workup of hypercalcemia. The diagnostic workup for patients presenting with hypercalcemia rests
Diagnostic algorithm ... for the workup ... sensitivity for correct classification ... #Differential # ... Algorithm
Humoral Immunity - Pathogenesis and Clinical Findings Antigens (Ag) are produced from pathogens (bacteria, viruses, fungi, parasites)
activation • Complement ... classical pathway (see ... Complement Activation ... proliferate and differentiate ... Humoral #Immunity #pathophysiology
Lab patterns seen in Inborn Errors of Metabolism A table of lab values compiled from UpToDate and
See IEM schema for ... metabolicemergency-pathophysiology-differential-pediatrics-metabolism-algorithm-diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Diagnosis Algorithm ... Lymphoproliferative #Disorders #Classification ... #pathophysiology ... #algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... genotypes): SS, SC, SE ... #Diagnosis #Algorithm ... #workup #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... permanent alopecia Differential ... RNP antibodies, Complement ... : Drug induced SLE
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