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diagnosis rheumatology differential types vasculitis allergy erythematosus hypersensitivity lupus reactions table champs clinical comparison criteria cryoglobulinemia cryoglobulins eularacr granuloma hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Post/pauci immune glomerulonephritis ... (>90%) S - Systemic ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Approach to managing Glomerulonephritis (GN) in children. ANCA, antineutrophil cytoplasmic antibodies; c-ANCA, cytoplasmic antineutrophil cytoplasmic antibodies;
cytoplasmic antibodies; SLE ... , systemic lupus ... #Glomerulonephritis ... #Algorithm #Nephrology ... #Peds #Pediatrics
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... Complement activation ... Post-streptococcal glomerulonephritis ... arthritis, and systemic ... Hypersensitivity #Types #Classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... anticoagulant • Complement ... #Criteria #SLE ... #Systemic #Lupus
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... Skin ulcers - Glomerulonephritis ... • Low serum C4 complement ... erythematosus (SLE ... diagnosis #types #classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
antigens, leading to complement ... they activate complement ... Post-streptococcal glomerulonephritis ... , Systemic lupus ... allergy #table #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... , pauci-immune glomerulonephritis ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic ... Mononeuropathy, Glomerulonephritis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... RNP antibodies, Complement ... #Systemic #Lupus
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Cytopenia: 2% • Hypocomplementemia ... Central nervous system ... acidosis • NAGMA • Glomerulonephritis ... Cytopenia: 2% Systemic
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