14 results
diagnosis rheumatology classification differential management comparison hypersensitivity lupus pathophysiology reactions vasculitis abpa allergic antibiotics aspergillosis bronchopulmonary champs clinicopathology cryoglobulinemia cryoglobulins
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... antigen, leading to complement ... Complement activation ... arthritis, and systemic ... Diagnosis #Reactions #Table
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... glomerulonephritis (>90%) S - Systemic ... #Low #Complement
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... antigens, leading to complement ... they activate complement ... glomerulonephritis, Systemic ... #allergy #table
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
Type III Hypersensitivity ... the cause: • Systemic ... Erythematosus (SLE ... sickness #TypeIII #Type3 ... HypersensitivityReaction #Allergy
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... diseases: - 10% SLE ... • Low serum C4 complement ... disorder (e.g. systemic ... erythematosus (SLE
Eosinophilia - Differential Diagnosis Algorithm Idiopathic Eosinophilia Primary Eosinophilia: • Primary hypereosinophilic syndrome • Eosinophilic Leukemia • MPN/MDS
Differential Diagnosis Algorithm ... B-cell lymphomas), Systemic ... histiocytosis • Allergic ... , Sarcoidosis, SLE ... #allergy
Penicillin Allergy Pathway for Antibiotic Prescription in Patients With Penicillin Allergy Mild Reaction - Itching, Minor rash
Maculopapular rash (mild type ... Use carbapenem Type ... Type II-IV HSR ... rash eosinophilia systemic ... #Prescription #algorithm
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... months to years) Systemic ... 80% - Low complement ... #comparison #table
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
infections include systemic ... See below for table ... helpful paper complements ... #Differential #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... central nervous system ... against MPO • Complement ... vasculitis, and SLE
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