7 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... central nervous system ... against MPO • Complement ... vasculitis, and SLE
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... RNP antibodies, Complement ... • Kidney biopsy ... #Systemic #Lupus
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Diagnosis: • Systemic ... diseases, such as SLE ... ESR > 50mm/hr • Biopsy ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
associated with systemic ... erythematosus (SLE ... Perform Kidney Biopsy ... Nephritis #diagnosis #algorithm ... #biopsy #indications
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary gland) biopsy ... Cytopenia: 2% • Hypocomplementemia ... salivary gland) biopsy ... Central nervous system
Majocchi’s Granuloma due to Trichophyton rubrum 
This is GMS stain and culture of a skin biopsy
culture of a skin biopsy ... + tinea pedis Biopsy ... - Systemic Rx ... Competent and compromised ... rubrum #clinical #photo
Cutaneous Mucormycosis Eschar
30 M HIV cd4 10 VL 30k traumatic injury of arm few months ago
malnutrition, HIV, SLE ... use Dx: skin biopsy ... wide excision & systemic ... skin #clinical #photo