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diagnosis rheumatology differential lupus management vasculitis classification clinical comparison druginduced erythematosus gi granuloma ileitis indications majocchis microscopy nephritis nephrology photo
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... months to years) Systemic ... 80% - Low complement ... #comparison #table
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
infections include systemic ... See below for table ... helpful paper complements ... #Differential #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... central nervous system ... against MPO • Complement ... vasculitis, and SLE
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... anti-Smith Ab, low complements ... RNP antibodies, Complement ... • Kidney biopsy ... #Systemic #Lupus
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... diseases, such as SLE ... ESR > 50mm/hr • Biopsy ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE) SLE patient develops
associated with systemic ... erythematosus (SLE ... Perform Kidney Biopsy ... Nephritis #diagnosis #algorithm ... #biopsy #indications
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary gland) biopsy ... Cytopenia: 2% • Hypocomplementemia ... salivary gland) biopsy ... Central nervous system
Majocchi’s Granuloma due to Trichophyton rubrum This is GMS stain and culture of a skin biopsy
culture of a skin biopsy ... + tinea pedis Biopsy ... recommended as sole ... - Systemic Rx ... Competent and compromised
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