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diagnosis rheumatology anesthesia anesthesiology intraoperative workup differential lupus vasculitis cardiacarrest comparison crisis cryoglobulinemia cryoglobulins druginduced erythematosus hypertension hyperthermia malignant sjogrens
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... and Management ... Positive in 60-80% of cases ... 80% - Low complement ... #lupus #Systemic
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Discontinuation of causal ... months to years) Systemic ... 80% - Low complement ... Usual therapeutic management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... • They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... diagnosis #types #classification
Cardiac Arrest - Guidelines for Crises in Anaesthesia The probable cause is one or more of: something
Check breathing system ... valves working and system ... • See Boxes B ... CardiacArrest #Checklist ... #Diagnosis #Management
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia Unexplained increase in ETCO2 AND tachycardia AND increased
Guidelines for Crises ... other, more common causes ... Change breathing system ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia Hypertension is most commonly due to inappropriate depth of
entire breathing system ... hypercarbia as causes ... be diagnostic – see ... Intraoperative #Checklist ... #Diagnosis #Management
Intraoperative Bronchospasm - Guidelines for Crises in Anaesthesia ❶ Call for help and inform theatre team of
Guidelines for Crises ... perform a rapid systematic ... suspected airway see ... Intraoperative #Checklist ... #Diagnosis #Management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... Central nervous system ... Rheumatology #Diagnosis #Management
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