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diagnosis rheumatology differential erythematosus lupus vasculitis causes champs criteria cryoglobulinemia cryoglobulins eularacr high hyperkalemia management mnemonic polycythemia potassium sjogrens syndrome
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... 1 (50%-80%), type ... glomerulonephritis (>90%) S - Systemic ... #Low #Complement ... #differential #hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... pericarditis • Hematologic ... anticoagulant • Complement ... #Criteria #SLE
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... factor level • Low ... serum C4 complement ... #classification ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... complements and ... Skin Disease Classification ... Kikuchi disease • Type-I ... the context of primary
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... vasculitis, and SLE ... #classification
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... IV RTA, TYPE I ... Nephrogenic DI Hematologic
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Differential Diagnosis Algorithm ... frequently affected systems ... Better call hematology ... some time, let’s see ... levels: realllly low
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
erythematosus (SLE ... Pseudohypoaldosteronism type ... Primary adrenal ... Drug-associated: heparin, low-molecular-weight ... High #Potassium #Classification
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