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diagnosis rheumatology differential clinicopathology cryoglobulinemia cryoglobulins erythematosus gammopathy laboratory lupus management mgrs monoclonal significance sjogrens smallpox syndrome systemic vasculitides
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... against MPO • Complement ... , and SLE) • Urinalysis ... (Renal involvement ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... Types: • Type ... • Low serum C4 complement ... erythematosus (SLE ... #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulmonary and renal ... diseases, such as SLE ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic ... Uveitis, chorioretinitis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I ... APLA/LAC: • Renal ... RNP antibodies, Complement
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Cytopenia: 2% • Hypocomplementemia ... ) • Cutaneous vasculitis ... cirrhosis: 3%-20% Renal ... I) renal tubular
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
Gammopathy of Renal ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis ... Types of MGRS-Associated
6/02/2022 UPDATE: This assay is designed to detect non-variola orthopoxviruses, including monkeypox virus. It is not
should use this algorithm ... smallpox-diagnostic-algorithm-poster ... -pages.pdf *Real-time ... The type of specimen ... See table below
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