31 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... 90% - Low complement ... Discontinuation of causal ... ulcers, Lupus nephritis ... • Immunologic Workup
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... test, ANA (e.g., SLE ... primary hematologic disorder ... #Workup #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... ulcers, Lupus nephritis ... • Immunologic Workup ... Positive in 60-80% of cases ... 80% - Low complement
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... ) • Endocrine disorders ... dysfunction, and mood disorder ... endocarditis • Valvular disorders ... RNP antibodies, Complement
Causes of Excessive Daytime Sleepiness - Differential Diagnosis Algorithm
Insufficient Sleep
 • Poor Sleep Hygiene
 • Insomnia
Causes of Excessive ... Differential Diagnosis Algorithm ... Shift Work) Sleep ... Differential #Diagnosis #Algorithm ... #Causes
Causes of Secondary IgA Nephropathy - Differential Diagnosis Algorithm
 • GI disorders: Celiac disease, Crohn's disease,
Causes of Secondary ... Differential Diagnosis Algorithm ... • GI disorders ... spondylitis, RA, SLE ... #Nephropathy #Causes
Causes of Approach to Altered Level of Consciousness - Workup
Clinical Exam - Focal
 • Trauma
 •
Causes of Approach ... Consciousness - Workup ... Hemorrhage • See ... Refer to Blood Work ... #algorithm #Causes
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Post-strep GN, Lupus Nephritis ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
or alternative complement ... infections are common causes ... glomerular #testing #workup ... glomerulonephritis #nephrotic ... #nephritic #nephrology
Suggested diagnostic approach to a patient with exudative ascites. Low ascitic fluid protein should direct practitioners
syndrome as a cause ... Although nonhepatic causes ... obstruction, nephrotic ... ascites #diagnosis #workup ... #algorithm #differential