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diagnosis differential rheumatology types hypersensitivity oncology pathophysiology reactions syndrome table cardiology comparison cryoglobulinemia cryoglobulins dermatology diffuse diseases erythematosus gammopathy glomerulonephritis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
When the specific allergen ... antigen, leading to complement ... Complement activation ... glomerulonephritis, rheumatoid arthritis ... Hypersensitivity #Types #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
lgE causes mast-cell ... they activate complement ... Examples: Rheumatoid arthritis ... reactions #types #allergy ... #table #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
GCA (Giant Cell Arteritis ... tract, and often causes ... arthritis. ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... arthralgia, and arthritis ... • Low serum C4 complement ... diagnosis #types #classification
Causes of Headache - Differential Diagnosis Algorithm Primary: Tension, Migraine, Cluster Extracranial: Medications, Sinusitis, TMJ disorder, Cervicogenic, Glaucoma,
Causes of Headache ... Differential Diagnosis Algorithm ... Glaucoma, Giant cell arteritis ... Aneurysm, Hemorrhage, Vasculitis ... #algorithm
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... • Rheumatoid Arthritis ... • Acne • Allergy ... #Causes #Hematology
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
IgA Vasculitis – ... Activation of complement ... periumbilical region), nausea ... Arthralgia's (common), arthritis ... #HSP #IgA #Vasculitis
Interstitial Lung Diseases (ILD) Exposure-Related ILD (a.k.a. extrinsic allergic alveolitis): • Hypersensitivity pneumonitis, Farmer's lung, Bird
a.k.a. extrinsic allergic ... ILD caused by inhalation ... sclerosis, Rheumatoid arthritis ... Sarcoidosis • Vasculitis ... differential #pulmonary #causes
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