13 results
diagnosis differential causes hematology rheumatology workup anemia bruising classification glomerular glomerulonephritis hemolytic nephrology nephrotic abscess agglutinin cold cryoglobulinemia cryoglobulins cva
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Granulomatous disease ... atherosclerotic disease ... against MPO • Complement
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Differential Diagnosis Algorithm ... • Steroids • Vasculitis ... Coagulation #Bleeding ... Differential #Diagnosis #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Consider sickle cell disease ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... workup #hematology #testing
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • Autoimmune diseases ... • Low serum C4 complement ... • IgA vasculitis ... • Vasculitis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Disease ... Cryoglobulins (Vasculitic ... Positive Coombs testing ... post infectious setting ... temperatures by fixing complement
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Von Willebrand’s disease ... Von Willebrand disease ... Von Willebrand disease ... fibrinogen levels, and testing ... integrity == • Vasculitis
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... for glomerular disease ... or alternative complement ... of glomerular disease ... for ANCA-related vasculitis
Upper Gastronintestinal Bleed - Differential Diagnosis Algorithm Acute Hematemesis/Melena - Blood in vomitus?/black, tarry stools - If
Differential Diagnosis Algorithm ... - Exclude bleeding ... Peptic Ulcer Disease ... - Stress (ICU Setting ... Differential #Diagnosis #Algorithm
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... for glomerular disease ... or alternative complement ... for ANCA-related vasculitis ... diagnosis #initial #testing
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