Hypocomplementemia complement vasculitis algorithm testing classification anemia workup mgrs

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Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Hemolytic Anemia ... Differential Diagnosis Algorithm ... cardiac valve, vasculitis ... #workup #hematology ... #testing

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Cryoglobulins (Vasculitic ... • Symptoms of anemia ... Positive Coombs testing ... significance (MGUS ... temperatures by fixing complement

Monoclonal Gammopathy of Renal Significance (MGRS)

MGRS
• MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins

) MGRS • MGRS ... Diagnostic Workup ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis

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