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differential hematology workup anemia disease glomerular nephrology nephrotic agglutinin causes extravascular glomerulonephritis hemolysis initial intravascular nephritic nephritis rheumatology vasculitides
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Algorithm Extravascular ... Warm AIHA • Cold ... perfringens - Complement-Mediated ... • Cold AIHA
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Diagnosis: • hemolytic ... Positive Coombs testing ... post infectious setting ... temperatures by fixing complement
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... Agglutination - Cold ... cardiac valve, vasculitis ... #hematology #testing
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... LDH - Assess for hemolysis ... or alternative complement ... for ANCA-related vasculitis ... #workup #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... LDH - Assess for hemolysis ... or alternative complement ... for ANCA-related vasculitis ... disease #workup #diagnosis
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