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diagnosis anemia disease hematology hemolytic nephrology pulmonary rheumatology agglutinin aki causes classification druginduced hsct kidneyinjury management medications prs stemcell syndrome
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
pulmonary and renal ... - Skin, glomeruli ... : - Kidneys: glomerular ... against MPO • Complement ... • Urinalysis (Renal
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... ANCA-positive vasculitis ... sclerosis • Anti-Glomerular ... Disease-specific testing ... #Syndrome #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Positive Coombs testing ... post infectious setting ... younger pts) Differential ... temperatures by fixing complement
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Injury • Pre-Renal ... Vitamin C • Glomerular ... : Drug induced vasculitis ... #KidneyInjury #differential ... #diagnosis #algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Diagnosis Algorithm ... Agglutination - Cold ... cardiac valve, vasculitis ... workup #hematology #testing
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... pulmonary and renal ... • Kidneys: Non-glomerular ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Autoimmune ANCA vasculitis ... palpable purpura 2/2 vasculitis ... of PRS: Biopsy (gold ... hypercellular glomeruli ... #Syndromes #differential
HSCT related renal disease - AKI and CKD Acute Kidney Injury: Acute GvHD 2-4, Pre renal state,
HSCT related renal ... Kidney Disease: • Glomerular ... body irradiation, Complement ... #disease #AKI #differential ... #diagnosis #algorithm
Weight Loss - Differential Diagnosis Algorithm Decreased Intake: • GI illness (upper and lower) • Psychiatric (Depression,
Weight Loss - Differential ... Diagnosis Algorithm ... Psychiatric (Depression, eating ... COPD) • Chronic ... Renal Failure
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