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diagnosis differential hyperthyroidism rheumatology testing glomerular glomerulonephritis hematology nephrology nephrotic anemia causes classification gammopathy hemolytic hypertension hyperthyroid igg4 indications initial
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Granulomatous disease ... atherosclerotic disease ... against MPO • Complement
Hyperthyroidism (low TSH, High T4/T3) - Diagnostic Algorithm Radioactive iodine scan – get if concern for nodular
) - Diagnostic Algorithm ... Graves disease – ... affects diagnostic workup ... Hyperthyroid #Diagnosis #Algorithm ... #Workup #Endocrinology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... Consider sickle cell disease ... cardiac valve, vasculitis ... Differential #Diagnosis #Algorithm ... #workup #hematology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... rheumatoid factor), ± hypocomplementemia ... No necrosis, No vasculitis ... IgG4 #Related #Disease ... management #phenotypes #workup
Approach to the Diagnosis of Hyperthyroidism - Differential Diagnosis and Workup Algorithm • Secondary Hyperthyroidism (↑↔TSH,
Diagnosis and Workup ... Algorithm • ... Uptake: • Graves disease ... trophoblastic disease ... #endocrinology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Differential Diagnosis Algorithm ... hematology for workup ... Rheumatologic, Vasculitides ... , IBD, Celiac disease ... Differential #Diagnosis #Algorithm
Approach to Thyroid Function Tests in the Evaluation of Hyperthyroidism • Low TSH, Low normal T4
Hyperthyroidism: Work-up ... ophthalmopathy → Graves' Disease ... Hyperthyroidism #algorithm ... #diagnosis #endocrinology
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
for glomerular disease ... or alternative complement ... of glomerular disease ... for ANCA-related vasculitis ... glomerular #testing #workup
Causes of Secondary Hypertension - Workup and Differential Diagnosis Approach (when evaluation should be done): 1. Severe or
Hypertension - Workup ... Coarctation of aorta, Vasculitis ... • Endocrinologic ... Renal parenchymal disease ... #Hypertension #Workup
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