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diagnosis rheumatology nephrology differential nephrotic testing workup acute aki disease erythematosus gammopathy glomerulonephritis igg4 injury lupus management mgrs monoclonal nephritic
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Skin, glomeruli ... : glomerular ischemia ... Kidneys -> glomerulonephritis ... against MPO • Complement ... #rheumatology #classification
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - Classification ... - Small vessel vasculitis ... - TTP/HUS • Glomerular ... #AKI #Acute #Kidney
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial ... evaluated for glomerular ... monitoring low-level glomerular ... or alternative complement ... for ANCA-related vasculitis
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial ... evaluated for glomerular ... or alternative complement ... for ANCA-related vasculitis ... workup #diagnosis #initial
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... musculoskeletal systems • Kidneys ... : Non-glomerular ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... RNP antibodies, Complement ... C4) • ds-DNA: Kidney ... induced SLE • Kidney
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
aortitis, mimics vasculitis ... • Kidneys: Tubulointerstitial ... - ↑ IgE, ↓ complement ... • Classification
Monoclonal Gammopathy of Renal Significance (MGRS) MGRS • MGRS refers to kidney disease caused by nephrotoxic monoclonal immunoglobulins
MGRS refers to kidney ... damage, especially kidneys ... guide subtype classification ... tubulopathy) - Complement ... formation causing vasculitis
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