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diagnosis rheumatology differential management medium size small cryoglobulinemia cryoglobulins cutaneous ddxof dermatology erythematosus glomerulonephritis im lupus mimics progressive pulmonary rapidly
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... Small #Medium #Large ... #Vessel #Size #Classification ... #ANCA #Differential ... #Algorithm #Ddxof
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
, arthritis LARGE ... Vessel Size: • Large ... against MPO • Complement ... , and SLE) • Urinalysis ... #rheumatology #classification
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
involvement by large ... Large vessel vasculitis ... affects large arteries ... basement membrane; ANCA ... #Classification
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis 90%: -
glomerulonephritis 90%: - ANCA ... Double Positive (ANCA ... anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... - Normal Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... discrepancies LARGE ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic ... chorioretinitis, CNS large
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis Involving ... 50% Cutaneous Vasculitis ... Secondary: CTD: SLE ... • ANCA Associated ... Polyarteritis nodosa Large
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... Vasculitis Vasculitis ... of large vessels ... small vessels - ANCA-associated ... dermatomyositis #Size #Classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... vasculitis, rheumatoid ... the small and large ... RNP antibodies, Complement
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... • Low serum C4 complement ... DDX: • ANCA (Antineutrophil ... erythematosus (SLE ... diagnosis #types #classification
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