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diagnosis rheumatology differential small disease management size vesselsize algorithm anca behcet behcets champs criteria cryoglobulinemia cryoglobulins cutaneous ddxof dermatology erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... , arthritis LARGE ... against MPO • Complement ... #rheumatology #classification
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology of Hypocomplementemic ... Urticarial Vasculitis ... Complex Formation - Complement ... Formation -> Vasculitis ... TerrierBen #Hypocomplementemic
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... Diagnosis #IM #Rheum #Vasculitis ... #Small #Medium ... #Large #Vessel # ... Size #Classification
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
involvement by large ... Large vessel vasculitis ... affects large arteries ... Medium vessel vasculitis ... #Large #Classification
Break down Vasculitis based on vessel size #Diagnosis #Rheumatology #Differential #Vasculitis #VesselSize #Small #Medium #Large #Classification
Break down Vasculitis ... #Differential #Vasculitis ... VesselSize #Small #Medium ... #Large #Classification
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... of large vessels ... of medium vessels ... Churg-Strauss syndrome ... dermatomyositis #Size #Classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
discrepancies LARGE ... primary condition MEDIUM ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic ... chorioretinitis, CNS large
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Vasculitis Involving ... Urticaria • Medium ... elevatum diutinum Medium ... Polyarteritis nodosa Large ... Disease • Cogan syndrome
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... Cryoglobulinemia Syndrome ... 20% Sjögren's syndrome ... • Low serum C4 complement ... diagnosis #types #classification
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