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diagnosis differential rheumatology aki injury nephrology causes disease igg4 management renal workup acutekidneyinjury anca cryoglobulinemia cryoglobulins ddxof erythematosus failure gammopathy
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... Diagnosis #IM #Rheum #Vasculitis ... #Small #Medium ... #Vessel #Size #Classification ... #Differential #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
abnormalities SMALL ... pain, infarct • Small ... Kidneys -> glomerulonephritis ... against MPO • Complement ... #rheumatology #classification
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - Classification ... emergency - Small ... vessel vasculitis ... #Kidney #Injury
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Causes of Acute ... Kidney Injury ( ... Glomerulonephritis Small-vessel ... vasculitis Acute ... #Kidney #Injury
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... • Limited to Kidney ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Emboli, Thrombosis, Vasculitis ... SCVMCMed #AKI #Acute ... #Kidney #Injury ... nephrology #causes #algorithm
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
false negative (small ... lesions, meninges, kidneys ... hypergammaglobulinemia, ↑ acute ... rheumatoid factor), ± hypocomplementemia ... No necrosis, No vasculitis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Low serum C4 complement ... • Cutaneous small-vessel ... vasculitis • ... • Vasculitis ... diagnosis #types #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... musculoskeletal systems • Kidneys ... and infarcts SMALL ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... Glomerulonephritis / Vasculits ... #Kidney #Injury ... #AKI #Workup #Algorithm
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