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diagnosis differential rheumatology nephrology acute aki injury kidney types workup acutekidneyinjury allergy anca champs comparison cryoglobulinemia cryoglobulins ddxof dermatology erythematosus
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Membranoproliferative glomerulonephritis ... Post/pauci immune glomerulonephritis ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
abnormalities SMALL ... tract, and often causes ... pain, infarct • Small ... against MPO • Complement ... #rheumatology #classification
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... Diagnosis #IM #Rheum #Vasculitis ... #Small #Medium ... #Vessel #Size #Classification ... #Differential #Algorithm
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... #Vasculitis #differential ... #diagnosis #algorithm
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Kidney Injury - Classification ... emergency - Small ... vessel vasculitis ... Post-infectious glomerulonephritis ... tubular necrosis (causes
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Skin ulcers - Glomerulonephritis ... • Low serum C4 complement ... • Cutaneous small-vessel ... diagnosis #types #classification
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
and infarcts SMALL ... (Glomerulonephritis ... tract, and often causes ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Causes of Acute Kidney Injury ( AKI ) - Prerenal, Renal, and Postrenal PRE-RENAL Impaired perfusion: •
Causes of Acute ... occlusion RENAL Glomerulonephritis ... Small-vessel ... vasculitis Acute
Vascular Skin Lesions - Differential Diagnosis Algorithm - Petechiae < 0.2 cm diameter - Purpura 0.2
Differential Diagnosis Algorithm ... with Pressure - Small ... • Acquired - Vasculitis ... #Vascular #Vasculitis ... #causes
Guide to Acute Kidney Injury (AKI) What to ask/look for: - HPI, PMH, full ROS
rhabdo/TLS) Causes ... related) - Glomerulonephritis ... or vasculitis — ... Nephrology #Diagnosis #Algorithm ... #Causes #Differential
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