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differential hematology testing causes rheumatology workup allergy anemia c1inh champs classification disease esterase extravascular fever hemolysis hemolytic igg4 immunecompromised immunocompromised
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
pseudotumor 4 phenotypes ... PET-CT Imaging (→ Diagnostic ... rheumatoid factor), ± hypocomplementemia ... Related #Disease #diagnosis ... #management #phenotypes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
- Differential Diagnosis ... Algorithm Extravascular ... • PK deficiency ... perfringens - Complement-Mediated ... #Algorithm #Causes
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... disease (diverse genotypes ... #Differential #Diagnosis ... #Algorithm #workup
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Differential Diagnosis ... against MPO • Complement
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... deficiency • Low ... #Algorithm #hematology ... #diagnosis
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm INDICATIONS FOR TESTING: • Recurrent angioedema (without urticaria) •
Complement 1 esterase ... inhibitor (C1-INH) Deficiency ... Testing Algorithm ... #Testing #Algorithm ... #allergy #diagnosis
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
- Differential Diagnosis ... Algorithm Structural ... Periodontal Disease Complement ... Deficiency • ... #Algorithm #Causes
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