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hematology disease workup differential anemia celiac deficiency gastroenterology hemolytic management rheumatology agglutinin allergy antiphospholipid apls autoimmune c1inh champs classification coccidioidomycosis
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
pseudotumor 4 phenotypes ... PET-CT Imaging (→ Diagnostic ... rheumatoid factor), ± hypocomplementemia ... Related #Disease #diagnosis ... #management #phenotypes
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Differential Diagnosis ... against MPO • Complement
Celiac Disease Testing Algorithm INDICATIONS FOR TESTING: Nonspecific symptoms (iron-deficiency anemia, failure to thrive, fever, skin
Algorithm INDICATIONS ... tTG IgA • tTG IgG ... and DGP IgGa • ... EMA IgG by IFA ... #Algorithm #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... Algorithm • Sickle ... disease (diverse genotypes ... #Algorithm #workup ... #hematology #testing
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... #Deficiency #Testing ... #Algorithm #hematology ... #diagnosis
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm INDICATIONS FOR TESTING: • Recurrent angioedema (without urticaria) •
Complement 1 esterase ... Algorithm INDICATIONS ... ARUPLabs #C1INH #Complement ... #Algorithm #allergy ... #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Diagnosis: • hemolytic ... Positive Coombs testing ... post infectious setting ... Donath-Landsteiner (IgG ... temperatures by fixing complement
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Syndrome (APLS) Testing ... Hypercoagulable Workup Algorithm ... INDICATIONS FOR TESTING ... Hypercoagulable #Workup #Algorithm ... #diagnosis #hematology
Autoimmune Hepatitis - Testing Algorithm Individual Tests: • F-Actin (Smooth Muscle) Antibody, IgG by ELISA with Reflex
Autoimmune Hepatitis - Testing ... Algorithm Individual ... Muscle) Antibody, IgG ... Autoimmune #Hepatitis #Algorithm ... #diagnosis #hepatology
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