13 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... Complement: Post-strep ... Idiopathic • Normal Complement ... differential #diagnosis #algorithm
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
in >90% - Low ... complement - Rare ... Discontinuation of causal ... 60-80% - Low ... complement - 50
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Positive in 60-80% of cases ... 60-80% - Low ... complement - 50 ... life-threatening • Treatment
The algorithm below shows how pre-test probability could be combined with various criteria to determine which
shows how pre-test ... patient with a low ... short course of treatment ... provide empiric treatment ... HSV PCR would cause
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
mental status and low ... & Dry) is the treatment ... the determined cause ... & Dry” is the treatment ... #differential #algorithm
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... Xerostomia • Dental caries ... Adenocarcinoma Treatment
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
coronary blood flow ... treat the primary cause ... may not be the case ... #diagnosis #algorithm ... criticalcare #foamed #treatment
Treatment algorithm for malignancy-associated hypercalcemia.
Hypercalcemia
 - Renal Failure → Dialysis with low Ca++ bath
Aggressive IV hydration
Treatment algorithm ... Dialysis with low ... Calcitonin Refractory Cases ... hypercalcemia #Treatment ... #algorithm #management