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diagnosis rheumatology vasculitis hematology large medium small champs ddxof disorders erythematosus glomerulonephritis im low lupus lymphomas lymphoproliferative mnemonic nonhodgkin pathophysiology
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... Mnemonic #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Findings by Vessel Size ... against MPO • Complement ... #rheumatology #classification
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
Large #Vessel #Size ... #Classification ... #ANCA #Differential ... #Algorithm #Ddxof
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... (C-ANCA): GPA > ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic ... #Vasculitis #Differential
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
based on vessel size ... can affect any size ... basement membrane; ANCA ... #Rheumatology #Differential ... Medium #Large #Classification
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Diagnosis Algorithm ... usually at a single site ... Lymphoproliferative #Disorders #Classification ... #algorithm
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... RNP antibodies, Complement
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