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diagnosis rheumatology differential vasculitis allergy erythematosus hypersensitivity lupus reactions systemic table causes champs clinicopathology comparison criteria cryoglobulinemia cryoglobulins eularacr fetal
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
Hypersensitivity Types ... , seasonal hay fever ... antigen, leading to complement ... Complement activation ... #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... vasculitis, and SLE ... #rheumatology #classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of types ... Anaphylaxis, Hay fever ... antigens, leading to complement ... they activate complement ... allergy #table #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... Types: • Type ... • Low serum C4 complement ... erythematosus (SLE ... #classification
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Constitutional domain: Fever ... anticoagulant • Complement ... #EULARACR #Classification ... #Criteria #SLE
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... Vasculitis: • Fevers ... and branches • Fever ... Elevated AST ALT • Hypocomplementemia ... Vasculitis) • Hypocomplementemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I ... to: Arthritis, Fever
Factors that May Affect Fetal Oxygenation - Differential Diagnosis Algorithm Excessive Uterine Activity: • Hyperstimulation • Placental
Differential Diagnosis Algorithm ... Conditions: • Fever ... Vasculopathy (SLE ... , Type 1 diabetes ... Differential #Diagnosis #Algorithm
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... IV RTA, TYPE I ... nephritis • Distal (Type
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